Correlation Between Cerebral Venous-Arterial Pco2 Difference With Jugular Venous Oxygen Saturation As Global Cerebral Ischemia in Severe Traumatic Brain Injury

Introduction Traumatic Brain Injury (TBI) remains a leading cause of morbidity and disability and is considered a major public health concern. Ischemia is considered a relevant factor in TBI for prognosis, but its diagnosis in the early phases is still a problem. Now jugular venous oxygen saturation (SjVO2) is used to evaluate blood flow and cerebral metabolic rate as well as the cerebral venous-arterial pCO2 difference (VADpCO2) as a marker of low cerebral blood flow. Besides, there’s no statement of VADpCO2 to guide medical therapy, consider as a not specific for global cerebral ischemia, but its observation over time may be useful.